Juvelook and Juvelook Volume
Juvelook is a Korean injectable that combines porous poly-D,L-lactic acid (PDLLA) particles with non-cross-linked hyaluronic acid. The standard vial is used as a skin booster for texture and fine lines; Juvelook Volume carries four times as much PDLLA for deeper, gradual support. Both sit under one Class 4 licence from Korea’s MFDS, and neither has a US FDA record.
Written by the Seoul Skin Boosters editorial team and medically reviewed by a Korean Board-Certified Dermatologist (AAD International Fellow · ASLMS member). Last reviewed: .
What is Juvelook made of?
Juvelook is made by Vaim Co., Ltd. in Korea. The manufacturer’s technology page describes spherical, porous PDLLA microparticles carried in non-cross-linked hyaluronic acid gel (checked 18 October 2026). The hyaluronic acid gives the injection its body; the PDLLA particles are the part meant to prompt new collagen as they slowly break down.
PDLLA belongs to the same polylactic acid family as Sculptra’s poly-L-lactic acid (PLLA), but it is a different form of the polymer, and the two products are not interchangeable. Results with collagen stimulators build gradually: the manufacturer describes Juvelook as promoting collagen “slowly and naturally”, and Juvelook Volume as giving an initial effect with results that “develop progressively over time” (product page).
Juvelook vs Juvelook Volume: what is the difference?
| Product | PDLLA + HA per vial | Uses listed by the manufacturer |
|---|---|---|
| Juvelook | 42.5 mg + 7.5 mg | Full-face skin rejuvenation, tear trough, acne scars, facial lines |
| Juvelook Volume (also sold as Lenisna) | 170 mg + 30 mg | Acne scars, forehead, temples, nasolabial folds, facial sagging |
| Juvelook i | 25.5 mg + 4.5 mg | Eye-area skin |
Figures come from the manufacturer’s English site, which is marked “for export only”. In practice the standard vial is used across the skin like a booster (Delight Dermatology Clinic lists it in 3 cc and 4 cc preparations), while Juvelook Volume is used where deeper, gradual support is wanted. Ask how many vials, and what preparation volume, your plan uses.
Is Juvelook licensed in Korea?
Yes. In the MFDS medical device database, Vaim holds a Class 4 licence for a “tissue-repair material”, permit 제허17-972호, dated 21 December 2017 (checked 18 October 2026). The brand names under that permit include Juvelook, Juvelook Volume, Lenisna, Juvelook i, Juvelook G and Juvelook Skin.
The licence wording is narrower than the manufacturer’s list of uses: polylactide and hyaluronic acid injected under the skin “to temporarily improve facial wrinkles in adults”. In the United States, the FDA’s premarket approval, 510(k) and De Novo databases held no Juvelook record on the same date.
What does the evidence show for Juvelook?
Most published work is small and uncontrolled. In a prospective study of 15 women treated for under-eye hollows with three sessions of the standard 50 mg product, investigator-rated improvement scores moved from 2.93 after the first session to 2.13 after the third (lower is better), skin elasticity, hydration and radiance scores improved, and no adverse events were reported [1]. We found no large randomised trial of Juvelook in PubMed comparable to those behind SKINVIVE or Sculptra.
What are the risks of Juvelook?
Expect the usual short-term effects of injections: redness, swelling, bumps and bruising. The serious risk shared by all particle-based injectables is accidental injection into a blood vessel. A systematic review of collagen stimulators counted one reported case of visual loss after a PDLLA-HA product and two after a PDLLA product carried in carboxymethylcellulose [2]. An expert panel has published a consensus on safe technique and emergency management specifically for PDLLA-HA 200, the strength sold as Juvelook Volume and Lenisna [3].
Ask whether your injector uses a cannula or needle in higher-risk areas such as the forehead, temples and around the nose, and what they keep on hand for a vascular emergency.
How much does Juvelook cost in Seoul?
| Treatment | Price range |
|---|---|
| Juvelook skin booster, 3 cc | KRW 150,000–300,000 |
| Juvelook booster, 4 cc | KRW 200,000–350,000 |
| Juvelook Volume, 1 vial | KRW 500,000–700,000 |
Prices checked 2026-10-18; confirm at consultation. Collagen stimulators are usually planned as a course, so ask for the total for the number of sessions proposed.
Is Juvelook the same as Sculptra?
No. Both are polylactic acid collagen stimulators, but Juvelook uses PDLLA with hyaluronic acid and is licensed in Korea, while Sculptra uses PLLA and holds FDA premarket approval. They differ in particles, preparation and evidence; see Sculptra vs Rejuran for how Sculptra compares with boosters.
Is Juvelook Volume a filler?
It sits between the two. Its hyaluronic acid gives some immediate fullness, but the larger PDLLA dose is meant to build support gradually, which is why it is placed deeper than a booster.
Can Juvelook be used for acne scars?
The manufacturer lists acne scars among Juvelook’s uses, but the Korean licence names facial wrinkles, and published scar data are limited to small series. Ask your dermatologist how they would combine it with other scar treatments.
How long does Juvelook last?
We found no long-term controlled data that gives a reliable figure. The manufacturer describes results as long-lasting without stating a timeframe, so ask your dermatologist how often they plan maintenance.
References
Bibliographic records retrieved from PubMed (U.S. National Library of Medicine).
Young SM, Lau EKH. Hybrid Biostimulator and Hyaluronic Acid Injectable for Tear Trough Rejuvenation. Aesthetic Plast Surg. 2026;50(13):5337-5343.
PubMed: 42098500Young SM, Goh ASC, Jeyabal P, Ooi ASH. Visual Loss in Biostimulator Injectables: A Review of Incidence, Risk Factors, Etiology and Management Proposal. Aesthetic Plast Surg. 2026;50(5):1994-2005.
PubMed: 41263987Lau KHE, Young S, Goh A, et al. Consensus Opinion on Safe Injection Technique and Management of PDLLA-HA200-Induced Visual Impairment. J Craniofac Surg. 2026;37(5):1103-1109.
PubMed: 41359890